Reply to: comparative effectiveness medicines research cannot assess efficacy
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چکیده
منابع مشابه
An Approach to Assess Generalizability in Comparative Effectiveness Research
Table B5: Results of the placebo test (figures are for the incidence rate ratio for the trial controls vs. non-participants and 95% confidence intervals, except for mortality, where figures are for the odds ratio) Generalized linear modeling Time series Emergency admissions per head Primary care contacts per head 0.92 (0.87, 0.97) 0.92 (0.87, 0.98) Mortality 2.17 (1.16, 4.08) n/a Note: Time ser...
متن کاملProspective observational studies to assess comparative effectiveness: the ISPOR good research practices task force report.
OBJECTIVE In both the United States and Europe there has been an increased interest in using comparative effectiveness research of interventions to inform health policy decisions. Prospective observational studies will undoubtedly be conducted with increased frequency to assess the comparative effectiveness of different treatments, including as a tool for "coverage with evidence development," "...
متن کاملThe hazards of comparative effectiveness when we cannot effectively compare.
According to the Agency for Health Care Research and Quality, “comparative effectiveness research is designed to inform health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options” (1). The data derived from clinical registries play an important role in assessing the effectiveness and appropriateness of various treatments, and their use i...
متن کاملHow to Assess the Value of Medicines?
This study aims to discuss approaches to assessing the value of medicines. Economic evaluation assesses value by means of the incremental cost-effectiveness ratio (ICER). Health is maximized by selecting medicines with increasing ICERs until the budget is exhausted. The budget size determines the value of the threshold ICER and vice versa. Alternatively, the threshold value can be inferred from...
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ژورنال
عنوان ژورنال: Journal of Clinical Epidemiology
سال: 2017
ISSN: 0895-4356
DOI: 10.1016/j.jclinepi.2017.09.009